Dipeptidyl peptidase I for efficient cleavage of His-Tags

UNIZYME Laboratories develop and produce proteins with main focus on dipeptidyl peptidase I (DPPI; cathepsin C) for use in downstream processing, peptide synthesis and drug discovery.

TAGZyme is a DPPI-based enzymatic system for the efficient production and affinity purification of therapeutic proteins using his-tags and tag removal. Using TAGZyme, precise removal of N-terminal his-tags is obtained without the risk of degradation of the target protein. Using TAGZyme, it is possible to go from identification of target directly into production, thus reducing development time and costs.

TAGZyme is widely applicable in research for the purification of his-tag proteins. For research purposes, please find product and ordering information at the Qiagen TAGZyme page. For all other applications of TAGZyme e.g., manufacturing of therapeutic proteins, please contact us (see products).

For TAGZyme troubleshooting, please send an email here.

UNIZYME has set up PROZYMEX A/S with a view to further commercialize the IPR and know-how related to DPPI and novel DPPI inhibitors (more information here).

Marts 2010